1.高效食品酶反应器创制
（1）食品酶反应器纳米载体材料设计与制备；
（2）食品酶反应器的催化机制研究；
2.食品功能因子绿色制备
3.食品组分新分析方法建立
4.营养素递送系统的构建

1. 国家自然科学基金面上项目，31872896，界面原位亲疏水可调的脂肪酶二维纳米反应器的构建及催化机理研究，主持。
2. 安徽省自然科学基金杰青项目（重点资助），2202085J04，食品酶催化方法与技术，主持
3. 合肥市共性关键技术研发“揭榜挂帅”项目，油料健康食品创制与品质提升关键技术，主持
4. 中国科学技术协会“青年人才托举工程”，2017QNRC001，主持

代表性论文
1. Zhang, Shan; Deng, Qianchun; Shangguan, Huijuan; Zheng, Chang; Jie, Shi;*(通讯作者) Huang, Fenghong; Tang, Bo ; Design and Preparation of Carbon Nitride-Based Amphiphilic Janus N-Doped Carbon/MoS2 Nanosheets for Interfacial Enzyme Nanoreactor, ACS Applied Materials & Interfaces, 2020, 12(10): 12227-12237 S ;

2. Jie, Shi;*(通讯作者) Zhang, Shan; Deng, Qianchun; Li, Ya; Geng, Zhigang; Zheng, Lei; Tang, Bo ; A versatile biocatalytic nano-platform based on Fe3O4-filled and zirconia shrunk holey carbon nanotubes, Chemical Engineering Journal, 2020, 402: 125737

3. Zhang, Shan; Hou, Huaqing; Zhao, Baozhu; Zhou, Qi; Tang, Rongfeng; Chen, Lin; Mao, Jin; Deng, Qianchun; Zheng, Lei; Jie, Shi;*(通讯作者); Hollow Mesoporous Carbon-Based Enzyme Nanoreactor for the Confined and Interfacial Biocatalytic Synthesis of Phytosterol Esters, Journal of Agriculturaland Food Chemistry, 2023, 71(4): 2014-2025

4. Jie, Shi; Li, Ya; Li, Qianqian; Li, Zhen ; Enzyme-Responsive Bioprobes Based on the Mechanism of Aggregation-Induced Emission, ACS Applied Materials & Interfaces, 2018, 10(15): 12278-12294

5. Hou, Huaqing; Shangguan, Huijuan; Zhang, Shan; Wang, Lan; Deng, Qianchun; Shi, Jie;*(通讯作者) Zheng, Lei ; High-Efficiency Enzymatic Synthesis of Lutein Esters by a Graphenelike Mesoporous Carbon-Based Lipase Nanoreactor, ACS Food Science & Technology, 2022, 2022(2): 503-511

6. Shi, Jie; Deng, Qianchun; Wan, Chuyun; Zheng, Mingming; Huang, Fenghong*; Tang, Bo*; Fluorometric probing of the lipase level as acute pancreatitis biomarkers based on interfacially controlled aggregation-induced emission (AIE), Chemical Science, 2017, 8(9): 6188-6195.

7. Shi, Jie; Deng, Qianchun; Li, Ya; Zheng, Mingming; Chai, Zhaofei; Wan, Chuyun; Zheng, Zhe; Li, Lu; Huang, Fenghong*; Tang, Bo*; A Rapid and Ultrasensitive Tetraphenylethylene-Based Probe with Aggregation-Induced Emission for Direct Detection of α-Amylase in Human Body Fluids, Analytical Chemistry, 2018, 90(22): 13775-13782

8. Shi, Jie; Deng, Qianchun*; Li, Ya; Zheng, Zhe; Shangguan, Huijuan; Li, Lu; Huang, Fenghong*; Tang, Bo*; Homogeneous probing of lipase and alpha-amylase simultaneously by AIEgens, Chemical Communications, 2019, 55(45): 6417-6420.

专利
1.一种固定酶载体材料及其制备方法, 中国, ZL201610322517.1..

2.固定化酶、磁性碳材料及其制备方法, 中国, ZL201610324746.7.

3.一种固定化酶、固定化酶载体及其制备方法, 中国, ZL201610964102.4.

1.2015年获中华农业科技奖优秀创新团队奖；2020年获湖北省专利奖金奖
2.中国青年科技工作者协会第六届委员会农业科学专委会委员